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    ndufa3 NADH:ubiquinone oxidoreductase subunit A3 [ Danio rerio (zebrafish) ]

    Gene ID: 445122, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ndufa3provided by ZNC
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit A3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-18
    See related
    Ensembl:ENSDARG00000041400 AllianceGenome:ZFIN:ZDB-GENE-040801-18
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:100908
    Summary
    Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFA3 (NADH:ubiquinone oxidoreductase subunit A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ndufa3 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (5717761..5721383, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (5818135..5821757, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:dkey-283b15.2 Neighboring gene zgc:158689 Neighboring gene uncharacterized LOC137487832 Neighboring gene cholecystokinin a Neighboring gene trafficking protein, kinesin binding 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hepatotoxicity assessment of Rhizoma Paridis in adult zebrafish through proteomes and metabolome. Jia Z, et al. Biomed Pharmacother, 2020 Jan. PMID 31766101
    2. Aclonifen causes developmental abnormalities in zebrafish embryos through mitochondrial dysfunction and oxidative stress. Lee JY, et al. Sci Total Environ, 2021 Jun 1. PMID 33548715
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
    Names
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
    NP_001003516.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003516.3 → NP_001003516.2  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

      Status: VALIDATED

      Source sequence(s)
      CU302315, EH546667
      UniProtKB/TrEMBL
      A0A8M1N1B6
      Related
      ENSDARP00000119521.1, ENSDART00000136655.2
      Conserved Domains (1) summary
      pfam14987
      Location:2 → 83
      NADHdh_A3; NADH dehydrogenase 1 alpha subcomplex subunit 3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      5717761..5721383 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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