rhbg Rh family B glycoprotein [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rhbgprovided by ZNC
Official Full Name: Rh family B glycoproteinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9542
See related: Ensembl:ENSDARG00000009018 AllianceGenome:ZFIN:ZDB-GENE-030131-9542
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj85f07; zgc:56354; wu:fj85f07
Summary: Predicted to enable ammonium channel activity. Acts upstream of or within ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in basolateral plasma membrane and cytoplasmic vesicle membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including ball; gill; integument; retina; and yolk syncytial layer. Orthologous to human RHBG (Rh family B glycoprotein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (29265801..29277186, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (29331178..29342563, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Rhcg1 and Rhbg mediate ammonia excretion by ionocytes and keratinocytes in the skin of zebrafish larvae.
Title: Rhcg1 and Rhbg mediate ammonia excretion by ionocytes and keratinocytes in the skin of zebrafish larvae: H+-ATPase-linked active ammonia excretion by ionocytes.
is required to facilitate normal ammonia excretion in the zebrafish larva
Title: Nitrogen excretion in developing zebrafish (Danio rerio): a role for Rh proteins and urea transporters.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ammonium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables ammonium channel activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ammonium homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ammonium homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ammonium transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ammonium transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ammonium transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ammonium transporter Rh type B

Names: Rhesus blood group, B glycoprotein; rh family type B glycoprotein; rh type B glycoprotein; rhesus blood group family type B glycoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.