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    wdr21 WD repeat domain 21 [ Danio rerio (zebrafish) ]

    Gene ID: 393674, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wdr21provided by ZNC
    Official Full Name
    WD repeat domain 21provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040109-2
    See related
    Ensembl:ENSDARG00000110654 AllianceGenome:ZFIN:ZDB-GENE-040109-2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73069
    Summary
    Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to several human genes including DCAF4 (DDB1 and CUL4 associated factor 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See wdr21 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (28422544..28434014, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (3284952..3288548)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (28523819..28531099, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class H Neighboring gene zinc finger, FYVE domain containing 1 Neighboring gene double PHD fingers 3 Neighboring gene regulator of G protein signaling 6 Neighboring gene uncharacterized LOC137488659

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC73069

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat domain 21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200701.1 → NP_956995.1  WD repeat domain 21

      See identical proteins and their annotated locations for NP_956995.1

      Status: PROVISIONAL

      Source sequence(s)
      AY423032
      UniProtKB/TrEMBL
      Q6PC79
      Related
      ENSDARP00000155012.1, ENSDART00000182824.1
      Conserved Domains (3) summary
      COG2319
      Location:119 → 474
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:278 → 315
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:367 → 467
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      28422544..28434014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468379.2 → XP_021324054.1  WD repeat domain 21 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IMY2, A0A8M9PH68
      Related
      ENSDARP00000149987.1, ENSDART00000193381.1
      Conserved Domains (2) summary
      COG2319
      Location:119 → 472
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:278 → 315
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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