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    ube2l3a ubiquitin-conjugating enzyme E2L 3a [ Danio rerio (zebrafish) ]

    Gene ID: 415162, updated on 9-Dec-2024

    Summary

    Official Symbol
    ube2l3aprovided by ZNC
    Official Full Name
    ubiquitin-conjugating enzyme E2L 3aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2977
    See related
    Ensembl:ENSDARG00000112087 AllianceGenome:ZFIN:ZDB-GENE-030131-2977
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ube2l3; zgc:86727; wu:fc22h11
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be active in nucleus. Is expressed in blastomere; brain; paraxial mesoderm; and somite. Orthologous to human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ube2l3a in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (3133098..3138403, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (3052953..3058858)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene Ras protein-specific guanine nucleotide-releasing factor 2a Neighboring gene creatine kinase, mitochondrial 2a (sarcomeric) Neighboring gene hypermethylated in cancer 2 Neighboring gene phosphatidylinositol 4-kinase, catalytic, alpha a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 L3a
    Names
    ubiquitin-conjugating enzyme E2L 3
    NP_001002072.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002072.2NP_001002072.1  ubiquitin-conjugating enzyme E2 L3a

      See identical proteins and their annotated locations for NP_001002072.1

      Status: VALIDATED

      Source sequence(s)
      EH549097, EH570970, EH575166
      UniProtKB/TrEMBL
      A0A8M1MZS9, Q6IQK2
      Related
      ENSDARP00000148914.1, ENSDART00000183365.1
      Conserved Domains (1) summary
      pfam00179
      Location:6144
      UQ_con; Ubiquitin-conjugating enzyme

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      3133098..3138403 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394799.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      32311..38216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)