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    cd151l CD151 antigen, like [ Danio rerio (zebrafish) ]

    Gene ID: 402948, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cd151lprovided by ZNC
    Official Full Name
    CD151 antigen, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1868
    See related
    Ensembl:ENSDARG00000068629 AllianceGenome:ZFIN:ZDB-GENE-040426-1868
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77759
    Summary
    Predicted to be involved in cell migration. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including epidermis; notochord; pharynx; pronephric duct; and ventricular zone. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex. Orthologous to human CD151 (CD151 molecule (Raph blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See cd151l in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (30998678..31014354)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (31020424..31036100)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene methenyltetrahydrofolate synthetase domain containing Neighboring gene uncharacterized LOC137488298 Neighboring gene urate (5-hydroxyiso-) hydrolase a Neighboring gene growth arrest-specific 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity. Nishimura Y, et al. Front Pharmacol, 2015. PMID 26441656, Free PMC Article
    2. Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo. Dickmeis T, et al. Genome Res, 2004 Feb. PMID 14718378, Free PMC Article
    3. RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish. Yang D, et al. BMC Genomics, 2012 Jul 17. PMID 22805612, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77759

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CD151 antigen, like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205650.1 → NP_991213.1  CD151 antigen, like

      See identical proteins and their annotated locations for NP_991213.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065859
      UniProtKB/TrEMBL
      A0A8N1TWK9, Q6P031, X1WBL3
      Related
      ENSDARP00000127604.2, ENSDART00000154993.3
      Conserved Domains (2) summary
      cd03155
      Location:112 → 221
      CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:15 → 249
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      30998678..31014354
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009293634.4 → XP_009291909.1  CD151 antigen, like isoform X1

      See identical proteins and their annotated locations for XP_009291909.1

      UniProtKB/TrEMBL
      A0A8N1TWK9, Q6P031, X1WBL3
      Conserved Domains (2) summary
      cd03155
      Location:112 → 221
      CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:15 → 249
      Tetraspannin; Tetraspanin family
    Nucleotide Protein Strain
    Heading Accession and Version

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