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    cwc25 CWC25 spliceosome associated protein homolog [ Danio rerio (zebrafish) ]

    Gene ID: 406771, updated on 9-Dec-2024

    Summary

    Official Symbol
    cwc25provided by ZNC
    Official Full Name
    CWC25 spliceosome associated protein homologprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2817
    See related
    Ensembl:ENSDARG00000003382 AllianceGenome:ZFIN:ZDB-GENE-040426-2817
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ccdc49; fc11a02; flj20291l; zgc:55552; im:7140273; wu:fc11a02
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2-type spliceosomal complex. Orthologous to human CWC25 (CWC25 spliceosome associated protein homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cwc25 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (5709424..5723788, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (5797542..5811906, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene Mab-21 domain containing 2 Neighboring gene fibroblast growth factor 12a Neighboring gene neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2b Neighboring gene somatostatin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of U2-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-splicing factor CWC25 homolog
    Names
    coiled-coil domain containing 49
    pate
    pte

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213462.3NP_998627.1  pre-mRNA-splicing factor CWC25 homolog

      See identical proteins and their annotated locations for NP_998627.1

      Status: VALIDATED

      Source sequence(s)
      BX120016, EH432546, EH600550
      UniProtKB/TrEMBL
      Q6DRK6, Q7ZVW8
      Related
      ENSDARP00000091697.3, ENSDART00000100924.5
      Conserved Domains (2) summary
      pfam10197
      Location:1137
      Cir_N; N-terminal domain of CBF1 interacting co-repressor CIR
      pfam12542
      Location:67156
      CWC25; Pre-mRNA splicing factor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      5709424..5723788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)