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    b3gnt3.4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tandem duplicate 4 [ Danio rerio (zebrafish) ]

    Gene ID: 561172, updated on 9-Dec-2024

    Summary

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    Official Symbol
    b3gnt3.4provided by ZNC
    Official Full Name
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tandem duplicate 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8875
    See related
    Ensembl:ENSDARG00000058100 AllianceGenome:ZFIN:ZDB-GENE-030131-8875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    b3gnt3; wu:fk30b12; zgc:171538
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Is expressed in blood. Orthologous to human B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See b3gnt3.4 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (13630058..13642590, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (13592350..13603330, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:ch211-126g16.8 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tendem duplicate 2 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3, tandem duplicate 3 Neighboring gene very low-density lipoprotein receptor Neighboring gene novel protein similar to vertebrate pim oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos. Wong KS, et al. Dev Dyn, 2009 Jul. PMID 19504456
    2. Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. Cannon JE, et al. Mech Dev, 2013 Feb. PMID 23072875, Free PMC Article
    3. Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. Liongue C, et al. PLoS One, 2012. PMID 22412924, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC171538

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in poly-N-acetyllactosamine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4
    Names
    beta-3-galactosyltransferase-like
    NP_001103580.1
    XP_005166911.1
    XP_005166913.1
    XP_009302084.1
    XP_068079082.1
    XP_068079083.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110110.2 → NP_001103580.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4

      See identical proteins and their annotated locations for NP_001103580.1

      Status: VALIDATED

      Source sequence(s)
      CR786572
      UniProtKB/TrEMBL
      A0A8M1NG76, A8KB44
      Related
      ENSDARP00000075319.3, ENSDART00000080875.4
      Conserved Domains (1) summary
      cl21608
      Location:126 → 321
      Galactosyl_T; Galactosyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      13630058..13642590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222982.1 → XP_068079083.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

      UniProtKB/TrEMBL
      A0A8M1NG76, A8KB44

    2. XM_005166854.5 → XP_005166911.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

      See identical proteins and their annotated locations for XP_005166911.1

      UniProtKB/TrEMBL
      A0A8M1NG76, A8KB44
      Conserved Domains (1) summary
      cl21608
      Location:126 → 321
      Galactosyl_T; Galactosyltransferase

    3. XM_009303809.4 → XP_009302084.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

      See identical proteins and their annotated locations for XP_009302084.1

      UniProtKB/TrEMBL
      A0A8M1NG76, A8KB44
      Conserved Domains (1) summary
      cl21608
      Location:126 → 321
      Galactosyl_T; Galactosyltransferase

    4. XM_005166856.5 → XP_005166913.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

      See identical proteins and their annotated locations for XP_005166913.1

      UniProtKB/TrEMBL
      A0A8M1NG76, A8KB44
      Conserved Domains (1) summary
      cl21608
      Location:126 → 321
      Galactosyl_T; Galactosyltransferase

    5. XM_068222981.1 → XP_068079082.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3.4 isoform X1

      UniProtKB/TrEMBL
      A0A8M1NG76, A8KB44
    Nucleotide Protein Strain
    Heading Accession and Version

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