cyth1a cytohesin 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cyth1aprovided by ZNC
Official Full Name: cytohesin 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-657
See related: Ensembl:ENSDARG00000076742 AllianceGenome:ZFIN:ZDB-GENE-030131-657
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cyth1; pscd1; fb38g09; wu:fb38g09; zgc:152822
Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Is expressed in blastoderm. Orthologous to human CYTH1 (cytohesin 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (57462223..57578496, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (57391699..57508007, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj27c08.y1 (e-PCR)
- UniSTS:198930

fb3809 (e-PCR)
- UniSTS:187164

fb38g09.x1 (e-PCR)
- UniSTS:203180

fj86f07.x1 (e-PCR)
- UniSTS:200158

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within epiboly involved in gastrulation with mouth forming second	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of ARF protein signal transduction	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytohesin-1a

Names: cytohesin 1; pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214682.2 → NP_999847.1 cytohesin-1a

See identical proteins and their annotated locations for NP_999847.1

Status: VALIDATED

Source sequence(s)

CR792428

UniProtKB/TrEMBL

A0A8M1PQL7, A0A8M6Z3G1, Q6PW01

Related

ENSDARP00000006121.7, ENSDART00000003066.9

Conserved Domains (4) summary

cd01252
Location:261 → 379

PH_GRP1-like; General Receptor for Phosphoinositides-1-like Pleckstrin homology (PH) domain

pfam00169
Location:265 → 377

PH; PH domain

pfam01369
Location:64 → 246

Sec7; Sec7 domain

pfam17075
Location:10 → 83

RRT14; Regular of rDNA transcription protein 14