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    phf10 PHD finger protein 10 [ Danio rerio (zebrafish) ]

    Gene ID: 393628, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phf10provided by ZNC
    Official Full Name
    PHD finger protein 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1573
    See related
    Ensembl:ENSDARG00000070084 AllianceGenome:ZFIN:ZDB-GENE-040426-1573
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    XAP135; zgc:66233; zgc:85788
    Summary
    Predicted to enable metal ion binding activity. Predicted to act upstream of or within nervous system development. Predicted to be located in nucleus. Predicted to be part of npBAF complex. Orthologous to human PHF10 (PHD finger protein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See phf10 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (5978810..6001980)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (5850333..5873503)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene sprouty related EVH1 domain containing 2b Neighboring gene actin related protein 2b Neighboring gene family with sequence similarity 120 member B Neighboring gene deltaD

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of the PDCD2-TBP-PSMB1 region in vertebrates. Trachtulec Z, et al. Gene, 2004 Jun 23. PMID 15194198
    2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC66233

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of npBAF complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PHD finger protein 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200655.3 → NP_956949.3  PHD finger protein 10

      Status: VALIDATED

      Source sequence(s)
      BX629343, EH455901, EH481640
      UniProtKB/Swiss-Prot
      A5PMM9, Q6NWE1, Q6TGV9
      UniProtKB/TrEMBL
      A0A8M1PBJ6, Z4YI11
      Related
      ENSDARP00000093339.3, ENSDART00000102563.5
      Conserved Domains (2) summary
      cd15528
      Location:371 → 425
      PHD1_PHF10; PHD finger 1 found in PHD finger protein 10 (PHF10) and similar proteins
      cd15529
      Location:427 → 470
      PHD2_PHF10; PHD finger 2 found in PHD finger protein 10 (PHF10) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      5978810..6001980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NWE1.2 GenPept UniProtKB/Swiss-Prot:Q6NWE1

    Gene LinkOut

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