n4bp2 NEDD4 binding protein 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: n4bp2provided by ZNC
Official Full Name: NEDD4 binding protein 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-061103-451
See related: Ensembl:ENSDARG00000061451 AllianceGenome:ZFIN:ZDB-GENE-061103-451
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:153456
Summary: Predicted to enable endonuclease activity. Is expressed in axis; floor plate; and hypochord. Orthologous to human N4BP2 (NEDD4 binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (23372587..23393799)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (22681848..22703060)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables endonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: NEDD4-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079967.1 → NP_001073436.1 NEDD4-binding protein 2

See identical proteins and their annotated locations for NP_001073436.1

Status: PROVISIONAL

Source sequence(s)

BC125868

UniProtKB/TrEMBL

A0JMG4

Related

ENSDARP00000082092.5, ENSDART00000087658.6

Conserved Domains (6) summary

smart00463
Location:1610 → 1691

SMR; Small MutS-related domain

cd14279
Location:1453 → 1487

CUE; CUE domain found in ubiquitin-binding CUE proteins

cd14365
Location:61 → 101

CUE_N4BP2; CUE domain found in NEDD4-binding protein 2 (N4BP2) and similar proteins

pfam08590
Location:1543 → 1602

DUF1771; Domain of unknown function (DUF1771)

pfam13671
Location:381 → 514

AAA_33; AAA domain

cl17190
Location:381 → 510

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...