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    ckba creatine kinase, brain a [ Danio rerio (zebrafish) ]

    Gene ID: 564694, updated on 27-Dec-2024

    Summary

    Official Symbol
    ckbaprovided by ZNC
    Official Full Name
    creatine kinase, brain aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-902
    See related
    Ensembl:ENSDARG00000069752 AllianceGenome:ZFIN:ZDB-GENE-060929-902
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb02h12; fb62d04; fc14g11; zgc:92079; mg:cb02h12; wu:fb62d04; wu:fc14g11; zgc:154095
    Summary
    Predicted to enable ATP binding activity and creatine kinase activity. Predicted to act upstream of or within phosphocreatine biosynthetic process and phosphorylation. Is expressed in central nervous system; liver; myotome; and pleuroperitoneal region. Orthologous to human CKB (creatine kinase B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ckba in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (15682640..15702647, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (15551648..15569081, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882994 Neighboring gene MAP/microtubule affinity-regulating kinase 3a Neighboring gene tRNA methyltransferase 61A Neighboring gene BCL2 associated athanogene 5 Neighboring gene cytochrome c oxidase assembly factor 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC154095

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables creatine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity, transferring phosphorus-containing groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphocreatine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    creatine kinase, brain a
    NP_001070631.1
    XP_005156700.1
    XP_017214261.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077163.1NP_001070631.1  creatine kinase, brain a

      See identical proteins and their annotated locations for NP_001070631.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124538
      UniProtKB/TrEMBL
      A0A0R4IGD0, A0A0R4IU65, A0A8M1NB79, A0A8M6Z2B4, Q08BV6
      Related
      ENSDARP00000134063.2, ENSDART00000170689.2
      Conserved Domains (1) summary
      cd00716
      Location:16373
      creatine_kinase_like; Phosphagen (guanidino) kinases such as creatine kinase and similar enzymes

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      15682640..15702647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017358772.3XP_017214261.2  creatine kinase, brain a isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z2B4
    2. XM_005156643.5XP_005156700.1  creatine kinase, brain a isoform X2

      See identical proteins and their annotated locations for XP_005156700.1

      UniProtKB/TrEMBL
      A0A0R4IGD0, A0A0R4IU65, A0A8M1NB79, A0A8M6Z2B4, Q08BV6
      Related
      ENSDARP00000092517.3, ENSDART00000101741.5
      Conserved Domains (1) summary
      cd00716
      Location:16373
      creatine_kinase_like; Phosphagen (guanidino) kinases such as creatine kinase and similar enzymes