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    muc13b mucin 13b, cell surface associated [ Danio rerio (zebrafish) ]

    Gene ID: 799648, updated on 9-Dec-2024

    Summary

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    Official Symbol
    muc13bprovided by ZNC
    Official Full Name
    mucin 13b, cell surface associatedprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080220-61
    See related
    Ensembl:ENSDARG00000079647 AllianceGenome:ZFIN:ZDB-GENE-080220-61
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:175131
    Summary
    Predicted to be located in cell periphery and membrane. Orthologous to human MUC13 (mucin 13, cell surface associated). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See muc13b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (16106459..16122514)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (16057649..16073704)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene potassium inwardly rectifying channel subfamily J member 19b Neighboring gene zinc finger protein 281b Neighboring gene low density lipoprotein receptor-related protein 2b Neighboring gene MAGUK p55 scaffold protein 3b Neighboring gene protein phosphatase 1, regulatory subunit 3Cb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. An inventory of mucin genes in the chicken genome shows that the mucin domain of Muc13 is encoded by multiple exons and that ovomucin is part of a locus of related gel-forming mucins. Lang T, et al. BMC Genomics, 2006 Aug 3. PMID 16887038, Free PMC Article
    2. Gel-forming mucins appeared early in metazoan evolution. Lang T, et al. Proc Natl Acad Sci U S A, 2007 Oct 9. PMID 17911254, Free PMC Article
    3. Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required. Kopp R, et al. Physiol Genomics, 2010 Sep. PMID 20571107
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mucin-13b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001308550.1 → NP_001295479.1  mucin-13b precursor

      Status: VALIDATED

      Source sequence(s)
      CR752646, EH494017, EH520344
      UniProtKB/TrEMBL
      A0A8M1P1E7, A0A8M9QEF7, E7F116
      Related
      ENSDARP00000102897.2, ENSDART00000114174.5
      Conserved Domains (2) summary
      smart00179
      Location:162 → 188
      EGF_CA; Calcium-binding EGF-like domain
      pfam01390
      Location:201 → 283
      SEA; SEA domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      16106459..16122514
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480173.2 → XP_021335848.1  mucin-13b isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q8L3, A0A8M9QEF7, A0A8M9QMN9
      Conserved Domains (2) summary
      smart00179
      Location:161 → 187
      EGF_CA; Calcium-binding EGF-like domain
      pfam01390
      Location:200 → 282
      SEA; SEA domain
    Nucleotide Protein Strain
    Heading Accession and Version

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