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    mllt1a MLLT1 super elongation complex subunit a [ Danio rerio (zebrafish) ]

    Gene ID: 565484, updated on 9-Dec-2024

    Summary

    Official Symbol
    mllt1aprovided by ZNC
    Official Full Name
    MLLT1 super elongation complex subunit aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081105-45
    See related
    Ensembl:ENSDARG00000043185 AllianceGenome:ZFIN:ZDB-GENE-081105-45
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mllt1; si:dkey-240a9.4
    Summary
    Predicted to enable chromatin binding activity and lysine-acetylated histone binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mllt1a in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (20194156..20230661, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (20163167..20198613, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene FCH and mu domain containing endocytic adaptor 1 Neighboring gene regulatory factor X, 2 (influences HLA class II expression) Neighboring gene acyl-CoA synthetase bubblegum family member 2 Neighboring gene alkaline ceramidase 1 Neighboring gene myosin IF

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lysine-acetylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription elongation factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein ENL
    Names
    myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 a
    myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      20194156..20230661 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166938.5XP_005166995.1  protein ENL isoform X4

      UniProtKB/TrEMBL
      A0A8M2BEY9
      Conserved Domains (1) summary
      pfam03366
      Location:29109
      YEATS; YEATS family
    2. XM_009303913.4XP_009302188.1  protein ENL isoform X2

      UniProtKB/TrEMBL
      A0A8M3BBR5
      Conserved Domains (1) summary
      pfam03366
      Location:29109
      YEATS; YEATS family
    3. XM_688768.10XP_693860.6  protein ENL isoform X3

      UniProtKB/TrEMBL
      A0A8N7T7S1
      Conserved Domains (1) summary
      pfam03366
      Location:29109
      YEATS; YEATS family
    4. XM_009303912.4XP_009302187.1  protein ENL isoform X1

      UniProtKB/TrEMBL
      A0A8M3AV46, E9QEN8
      Related
      ENSDARP00000063399.5, ENSDART00000063400.7
      Conserved Domains (1) summary
      pfam03366
      Location:29109
      YEATS; YEATS family