dytn dystrotelin [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dytnprovided by ZNC
Official Full Name: dystrotelinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070124-2
See related: Ensembl:ENSDARG00000071025 AllianceGenome:ZFIN:ZDB-GENE-070124-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7155274
Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in synaptic signaling. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human DYTN (dystrotelin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (13116845..13133932)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (12883103..12900536)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in synaptic signaling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dystrotelin

Names: dyt

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080587.1 → NP_001074056.1 dystrotelin

See identical proteins and their annotated locations for NP_001074056.1

Status: PROVISIONAL

Source sequence(s)

DQ443726

UniProtKB/Swiss-Prot

A2CI97

Related

ENSDARP00000095514.1, ENSDART00000104744.3

Conserved Domains (4) summary

pfam09068
Location:9 → 118

EF-hand_2; EF hand

pfam09069
Location:122 → 217

EF-hand_3; EF-hand

pfam16515
Location:368 → 465

HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

cl00295
Location:226 → 274

ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

13116845..13133932

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009302235.4 → XP_009300510.1 dystrotelin isoform X1

See identical proteins and their annotated locations for XP_009300510.1

UniProtKB/Swiss-Prot

A2CI97

Conserved Domains (4) summary

pfam09068
Location:9 → 118

EF-hand_2; EF hand

pfam09069
Location:122 → 217

EF-hand_3; EF-hand

pfam16515
Location:368 → 465

HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

cl00295
Location:226 → 274

ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
XM_009302236.4 → XP_009300511.1 dystrotelin isoform X2

UniProtKB/TrEMBL

A0A8M3B0A4

Conserved Domains (4) summary

pfam09068
Location:8 → 117

EF-hand_2; EF hand

pfam09069
Location:121 → 216

EF-hand_3; EF-hand

pfam16515
Location:367 → 464

HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1

cl00295
Location:225 → 273

ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
XM_068221754.1 → XP_068077855.1 dystrotelin isoform X2

UniProtKB/TrEMBL

A0A8M3B0A4