tk1 thymidine kinase 1, soluble [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tk1provided by ZNC
Official Full Name: thymidine kinase 1, solubleprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5801
See related: Ensembl:ENSDARG00000102245 AllianceGenome:ZFIN:ZDB-GENE-030131-5801
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi19b06; zgc:55362; wu:fi19b06
Summary: Predicted to enable thymidine kinase activity. Predicted to be involved in thymidine metabolic process. Predicted to act upstream of or within DNA biosynthetic process and phosphorylation. Is expressed in several structures, including alar plate midbrain region; nervous system; optic vesicle; pectoral fin musculature; and proliferative region. Orthologous to human TK1 (thymidine kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (45153126..45159361)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (44738732..44743662)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fi19b06.x1 (e-PCR)
- UniSTS:196971

G45125 (e-PCR)
- UniSTS:105927

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables thymidine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables thymidine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in thymidine metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: thymidine kinase, cytosolic

Names: deoxyribonucleoside kinase

NP_956126.1

EC 2.7.1.21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.