fbxo45 F-box protein 45 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fbxo45provided by ZNC
Official Full Name: F-box protein 45provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1450
See related: Ensembl:ENSDARG00000071492 AllianceGenome:ZFIN:ZDB-GENE-040426-1450
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:65875
Summary: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and synapse assembly involved in innervation. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in synapse. Orthologous to human FBXO45 (F-box protein 45). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (28426540..28437828, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (28347381..28358669, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
involved_in synapse assembly involved in innervation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of SCF ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: F-box/SPRY domain-containing protein 1

Names: F-box only protein 45

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200595.1 → NP_956889.1 F-box/SPRY domain-containing protein 1

See identical proteins and their annotated locations for NP_956889.1

Status: PROVISIONAL

Source sequence(s)

BC056756

UniProtKB/Swiss-Prot

Q6NZ03, Q6PH10

Related

ENSDARP00000106584.2, ENSDART00000125412.3

Conserved Domains (2) summary

pfam12937
Location:44 → 90

F-box-like; F-box-like

cd12907
Location:117 → 291

SPRY_Fbox; SPRY domain in the F-box family Fbxo45