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    adgb androglobin [ Danio rerio (zebrafish) ]

    Gene ID: 555435, updated on 9-Dec-2024

    Summary

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    Official Symbol
    adgbprovided by ZNC
    Official Full Name
    androglobinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041001-205
    See related
    Ensembl:ENSDARG00000005595 AllianceGenome:ZFIN:ZDB-GENE-041001-205
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-170m15.2
    Summary
    Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in spermatid development. Predicted to act upstream of or within proteolysis. Predicted to be active in sperm annulus and sperm midpiece. Is expressed in olfactory placode and peripheral olfactory organ. Orthologous to human ADGB (androglobin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See adgb in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (31929424..32007137, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (32026590..32104076, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene SAM and SH3 domain containing 1a Neighboring gene uncharacterized LOC137488662 Neighboring gene syntaxin binding protein 5a (tomosyn) Neighboring gene RAB32a, member RAS oncogene family Neighboring gene glutamate receptor, metabotropic 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective. Coppola U, et al. BMC Evol Biol, 2016 Jan 27. PMID 26818140, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calpain-7-like protein; androglobin
    Names
    DKEY-170M15.3
    DKEY-170M15.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      31929424..32007137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_677935.9 → XP_683027.5  androglobin isoform X3

      UniProtKB/TrEMBL
      A0A8N7UUL0, F1QQ89
      Related
      ENSDARP00000009325.6, ENSDART00000021575.8
      Conserved Domains (2) summary
      cl00051
      Location:72 → 269
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cl21461
      Location:714 → 801
      Globin_like; Globin-like proteins

    2. XM_009294782.4 → XP_009293057.1  androglobin isoform X4

      UniProtKB/TrEMBL
      A0A8M3AWD7
      Conserved Domains (2) summary
      cl00051
      Location:72 → 269
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cl21461
      Location:678 → 765
      Globin_like; Globin-like proteins

    3. XM_009294781.4 → XP_009293056.1  androglobin isoform X2

      UniProtKB/TrEMBL
      A0A8M3ALN5
      Conserved Domains (2) summary
      cl00051
      Location:72 → 269
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cl21461
      Location:716 → 803
      Globin_like; Globin-like proteins

    4. XM_009294780.4 → XP_009293055.1  androglobin isoform X1

      UniProtKB/TrEMBL
      A0A8M3B490
      Conserved Domains (2) summary
      cl00051
      Location:72 → 269
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cl21461
      Location:716 → 803
      Globin_like; Globin-like proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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