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    fosl1b FOS like 1, AP-1 transcription factor subunit b [ Danio rerio (zebrafish) ]

    Gene ID: 793507, updated on 9-Dec-2024

    Summary

    Official Symbol
    fosl1bprovided by ZNC
    Official Full Name
    FOS like 1, AP-1 transcription factor subunit bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-259
    See related
    Ensembl:ENSDARG00000079373 AllianceGenome:ZFIN:ZDB-GENE-091204-259
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-17e16.12
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including blastodisc; epidermis; female organism; hatching gland; and male organism. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human FOSL1 (FOS like 1, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See fosl1b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (25614436..25619972, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (25577819..25582399, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene EGF containing fibulin extracellular matrix protein 2b Neighboring gene fibroblast growth factor (acidic) intracellular binding protein b Neighboring gene transmembrane protein 223 Neighboring gene ovo-like zinc finger 1b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    fos-related antigen 2
    Names
    FOS-like antigen 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      25614436..25619972 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009295436.4XP_009293711.1  fos-related antigen 2

      UniProtKB/TrEMBL
      A0A8M3B4T3, E9QHS1
      Related
      ENSDARP00000122100.1, ENSDART00000133512.2
      Conserved Domains (2) summary
      cd14686
      Location:128179
      bZIP; coiled coil [structural motif]
      cl21462
      Location:127188
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain