U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ccnt1 cyclin T1 [ Danio rerio (zebrafish) ]

    Gene ID: 334465, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ccnt1provided by ZNC
    Official Full Name
    cyclin T1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6397
    See related
    Ensembl:ENSDARG00000017525 AllianceGenome:ZFIN:ZDB-GENE-030131-6397
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi75b02; wu:fi75b02; si:dkey-18f23.10
    Summary
    Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of DNA-templated transcription, elongation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be part of cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Orthologous to human CCNT1 (cyclin T1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ccnt1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (35650762..35666658)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (35551969..35569755)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137489143 Neighboring gene transmembrane protein 18 Neighboring gene premelanosome protein b Neighboring gene tubulin, alpha 1c

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sun Y, et al. Sci Adv, 2019 Jun. PMID 31183407, Free PMC Article
    2. Oncogenic CDK13 mutations impede nuclear RNA surveillance. Insco ML, et al. Science, 2023 Apr 21. PMID 37079685, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cyclin-T1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256611.1 → NP_001243540.1  cyclin-T1

      Status: PROVISIONAL

      Source sequence(s)
      BC044435
      UniProtKB/TrEMBL
      A0A8M1P3I1, Q803K9
      Related
      ENSDARP00000027016.7, ENSDART00000005158.8
      Conserved Domains (1) summary
      pfam00134
      Location:16 → 152
      Cyclin_N; Cyclin, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      35650762..35666658
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162370.5 → XP_005162427.1  cyclin-T1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9H0, Q803K9
      Conserved Domains (1) summary
      pfam00134
      Location:16 → 152
      Cyclin_N; Cyclin, N-terminal domain

    2. XM_068216687.1 → XP_068072788.1  cyclin-T1 isoform X2

      UniProtKB/TrEMBL
      Q803K9
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools