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    bnip2 BCL2 interacting protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 394197, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bnip2provided by ZNC
    Official Full Name
    BCL2 interacting protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040109-6
    See related
    Ensembl:ENSDARG00000013397 AllianceGenome:ZFIN:ZDB-GENE-040109-6
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be involved in apoptotic process. Predicted to be active in cytoplasm. Orthologous to human BNIP2 (BCL2 interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See bnip2 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (34246625..34270943)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (33761008..33785338)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene annexin A2-A-like Neighboring gene forkhead box B1a Neighboring gene glucosaminyl (N-acetyl) transferase 3, mucin type Neighboring gene proprotein convertase subtilisin/kexin type 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Gene Expression of CRAL_TRIO Family Proteins modulated by Vitamin E Deficiency in Zebrafish (Danio Rerio). Watt AT, et al. J Nutr Biochem, 2021 Nov. PMID 34119630, Free PMC Article
    2. Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. Cañestro C, et al. PLoS Genet, 2009 May. PMID 19478994, Free PMC Article
    3. Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish. Hu P, et al. Sci Rep, 2016 Jun 30. PMID 27356472, Free PMC Article
    4. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
    5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
    Names
    BCL2/adenovirus E1B 19kDa interacting protein 2
    BCL2/adenovirus E1B interacting protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201218.1 → NP_957512.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

      See identical proteins and their annotated locations for NP_957512.1

      Status: PROVISIONAL

      Source sequence(s)
      AY423003
      UniProtKB/TrEMBL
      Q6TEP6
      Conserved Domains (2) summary
      cd00170
      Location:151 → 294
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
      pfam12496
      Location:52 → 167
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      34246625..34270943
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217349.1 → XP_068073450.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 isoform X3

    2. XM_009298160.4 → XP_009296435.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AP94, F1QHC0
      Related
      ENSDARP00000077013.4, ENSDART00000082578.6
      Conserved Domains (2) summary
      cd00170
      Location:283 → 426
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
      pfam12496
      Location:184 → 299
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2

    3. XM_009298162.4 → XP_009296437.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M3B7D1
      Related
      ENSDARP00000125066.1, ENSDART00000148507.3
      Conserved Domains (2) summary
      cd00170
      Location:283 → 426
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
      pfam12496
      Location:184 → 299
      BNIP2; Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
    Nucleotide Protein Strain
    Heading Accession and Version

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