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    rpap3 RNA polymerase II associated protein 3 [ Danio rerio (zebrafish) ]

    Gene ID: 393173, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rpap3provided by ZNC
    Official Full Name
    RNA polymerase II associated protein 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-928
    See related
    Ensembl:ENSDARG00000087962 AllianceGenome:ZFIN:ZDB-GENE-040426-928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56178
    Summary
    Is expressed in alar plate midbrain region; forerunner cell group; immature eye; and optic tectum. Orthologous to human RPAP3 (RNA polymerase II associated protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rpap3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (966061..983242)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (952613..969794)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene SIM bHLH transcription factor 1b Neighboring gene ATP23 metallopeptidase and ATP synthase assembly factor homolog Neighboring gene N-acetylgalactosaminidase, alpha Neighboring gene glutamate receptor ionotropic, kainate 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Duplicated zebrafish co-orthologs of parathyroid hormone-related peptide (PTHrP, Pthlh) play different roles in craniofacial skeletogenesis. Yan YL, et al. J Endocrinol, 2012 Sep. PMID 22761277, Free PMC Article
    2. Pharmacological modulation of melanocortin-4 receptor by melanocortin receptor accessory protein 2 in Nile tilapia. Wang M, et al. Gen Comp Endocrinol, 2019 Oct 1. PMID 31299224
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56178

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase II-associated protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200204.2 → NP_956498.2  RNA polymerase II-associated protein 3

      Status: VALIDATED

      Source sequence(s)
      FO904962
      UniProtKB/TrEMBL
      A0A8M1PAY5, F1R498
      Related
      ENSDARP00000107727.2, ENSDART00000122535.4
      Conserved Domains (5) summary
      sd00006
      Location:128 → 156
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:196 → 229
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:278 → 344
      TPR_11; TPR repeat
      pfam13432
      Location:172 → 230
      TPR_16; Tetratricopeptide repeat
      pfam13877
      Location:475 → 566
      RPAP3_C; Potential Monad-binding region of RPAP3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      966061..983242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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