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    klhdc3 kelch domain containing 3 [ Danio rerio (zebrafish) ]

    Gene ID: 406553, updated on 9-Dec-2024

    Summary

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    Official Symbol
    klhdc3provided by ZNC
    Official Full Name
    kelch domain containing 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2426
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040426-2426
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85727
    Summary
    Orthologous to human KLHDC3 (kelch domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See klhdc3 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (51978775..52002867)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (51769322..51778685)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase A Neighboring gene kinesin light chain 1b Neighboring gene protein tyrosine kinase 7b Neighboring gene solute carrier family 30 member 10 Neighboring gene lysocardiolipin acyltransferase 1 Neighboring gene transmembrane protein 121 Neighboring gene neuronal PAS domain protein 4 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Lieschke GJ, et al. Blood, 2001 Nov 15. PMID 11698295
    2. Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. Mattonet K, et al. Sci Adv, 2022 Sep 2. PMID 36044573, Free PMC Article
    3. Why does the zebrafish cloche mutant develop lens cataract? Posner M, et al. PLoS One, 2019. PMID 30861003, Free PMC Article
    4. Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish. Nakajima H, et al. Dev Cell, 2023 Feb 6. PMID 36693371
    5. Leukemia-associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis. Germano G, et al. Dev Dyn, 2022 Oct. PMID 35429189

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    kelch domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      51978775..52002867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480925.2 → XP_021336600.1  kelch domain-containing protein 3

      UniProtKB/TrEMBL
      A0A8M9QNZ4
      Conserved Domains (2) summary
      sd00038
      Location:128 → 173
      Kelch; KELCH repeat [structural motif]
      cl26061
      Location:9 → 198
      PLN02193; nitrile-specifier protein

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_213269.1: Suppressed sequence

      Description
      NM_213269.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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