unc119a1 unc-119 lipid binding chaperone a1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: unc119a1provided by ZNC
Official Full Name: unc-119 lipid binding chaperone a1provided by ZNC
Primary source: ZFIN:ZDB-GENE-090930-2
See related: Ensembl:ENSDARG00000034453 AllianceGenome:ZFIN:ZDB-GENE-090930-2
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rtg4; unc119; unc-119; unc119a; si:dkey-234f12.7
Summary: Predicted to enable lipid binding activity. Predicted to be involved in several processes, including lipoprotein transport; negative regulation of endocytosis; and visual perception. Predicted to act upstream of or within endocytosis and protein transport. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in intercellular bridge and microtubule cytoskeleton. Is expressed in several structures, including hematopoietic system; mesenchyme; olfactory pit; solid lens vesicle; and visual system. Human ortholog(s) of this gene implicated in cone-rod dystrophy 24 and immunodeficiency 13. Orthologous to human UNC119 (unc-119 lipid binding chaperone). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (28106534..28125423)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (28173664..28192473)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables lipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables lipid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within endocytosis	IEA Inferred from Electronic Annotation more info
involved_in lipoprotein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic cytokinesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of caveolin-mediated endocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of clathrin-dependent endocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in nervous system development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within visual perception	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in centrosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in intercellular bridge	IBA Inferred from Biological aspect of Ancestor more info
is_active_in spindle midzone	IBA Inferred from Biological aspect of Ancestor more info
is_active_in spindle pole	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain