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    mob3a MOB kinase activator 3A [ Danio rerio (zebrafish) ]

    Gene ID: 325366, updated on 9-Dec-2024

    Summary

    Official Symbol
    mob3aprovided by ZNC
    Official Full Name
    MOB kinase activator 3Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4091
    See related
    Ensembl:ENSDARG00000019113 AllianceGenome:ZFIN:ZDB-GENE-030131-4091
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc69e01; mobkl2a; zgc:56681; zgc:77552; wu:fc69e01
    Summary
    Predicted to enable protein kinase activator activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to several human genes including MOB3A (MOB kinase activator 3A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mob3a in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (20416112..20426652)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (20384027..20394567)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 10 Neighboring gene zeta chain of T cell receptor associated protein kinase 70 Neighboring gene MAPK interacting serine/threonine kinase 2b Neighboring gene REX1, RNA exonuclease 1 homolog

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    MOB kinase activator 3A
    Names
    MOB1, Mps One Binder kinase activator-like 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199716.1NP_956010.1  MOB kinase activator 3A

      See identical proteins and their annotated locations for NP_956010.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049527
      UniProtKB/TrEMBL
      Q7ZW91
      Related
      ENSDARP00000021765.6, ENSDART00000009081.9
      Conserved Domains (1) summary
      pfam03637
      Location:35207
      Mob1_phocein; Mob1/phocein family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      20416112..20426652
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)