pwp1 PWP1 homolog, endonuclein [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pwp1provided by ZNC
Official Full Name: PWP1 homolog, endonucleinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1049
See related: Ensembl:ENSDARG00000015921 AllianceGenome:ZFIN:ZDB-GENE-040426-1049
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56486
Summary: Predicted to act upstream of or within rRNA processing. Predicted to be active in nucleus. Orthologous to human PWP1 (PWP1 homolog, endonuclein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (1827050..1839192, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (1977737..1989879, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: periodic tryptophan protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200292.1 → NP_956586.1 periodic tryptophan protein 1 homolog

See identical proteins and their annotated locations for NP_956586.1

Status: PROVISIONAL

Source sequence(s)

BC049457

UniProtKB/TrEMBL

A0A8M1PCQ6, Q7ZWE1

Related

ENSDARP00000003237.6, ENSDART00000003790.7

Conserved Domains (3) summary

COG2319
Location:250 → 470

WD40; WD40 repeat [General function prediction only]

sd00039
Location:257 → 294

7WD40; WD40 repeat [structural motif]

cl02567
Location:250 → 412

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...