snrpe small nuclear ribonucleoprotein polypeptide E [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snrpeprovided by ZNC
Official Full Name: small nuclear ribonucleoprotein polypeptide Eprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1112
See related: Ensembl:ENSDARG00000033175 AllianceGenome:ZFIN:ZDB-GENE-040426-1112
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56682
Summary: Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to act upstream of or within mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleus. Predicted to be part of several cellular components, including U2-type spliceosomal complex; methylosome; and spliceosomal snRNP complex. Is expressed in head. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; hypotrichosis 1; hypotrichosis 11; and lupus nephritis. Orthologous to human SNRPE (small nuclear ribonucleoprotein polypeptide E). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (37720575..37726203)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (37453370..37458996)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fe01a10.x1 (e-PCR)
- UniSTS:195898

AW165072 (e-PCR)
- UniSTS:205886

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in spliceosomal snRNP assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in spliceosomal snRNP assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of SMN-Sm protein complex	ISS Inferred from Sequence or Structural Similarity more info
part_of U1 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U1 snRNP	ISS Inferred from Sequence or Structural Similarity more info
part_of U2 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type catalytic step 2 spliceosome	ISS Inferred from Sequence or Structural Similarity more info
part_of U2-type precatalytic spliceosome	ISS Inferred from Sequence or Structural Similarity more info
part_of U4 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U4 snRNP	ISS Inferred from Sequence or Structural Similarity more info
part_of U4/U6 x U5 tri-snRNP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U4/U6 x U5 tri-snRNP complex	ISS Inferred from Sequence or Structural Similarity more info
part_of U5 snRNP	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
part_of methylosome	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
part_of pICln-Sm protein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of pICln-Sm protein complex	ISS Inferred from Sequence or Structural Similarity more info
part_of precatalytic spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: small nuclear ribonucleoprotein E

Names: sm protein E; sm-E; smE; snRNP-E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.