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    hoxc12b homeobox C12b [ Danio rerio (zebrafish) ]

    Gene ID: 58062, updated on 9-Dec-2024

    Summary

    Official Symbol
    hoxc12bprovided by ZNC
    Official Full Name
    homeobox C12bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000329-17
    See related
    Ensembl:ENSDARG00000103133 AllianceGenome:ZFIN:ZDB-GENE-000329-17
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:eu246
    Summary
    Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in central nervous system; mesoderm; musculature system; neural rod; and post-vent region. Orthologous to human HOXC12 (homeobox C12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hoxc12b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (2172335..2173459)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (2132277..2133401, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene calcium binding and coiled-coil domain 1b Neighboring gene homeobox C13b Neighboring gene uncharacterized LOC100534851 Neighboring gene homeobox C11b Neighboring gene microRNA 196c Neighboring gene homeobox C6b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    homeobox protein Hox-C12b
    Names
    homeo box C12b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131545.1NP_571620.1  homeobox protein Hox-C12b

      See identical proteins and their annotated locations for NP_571620.1

      Status: PROVISIONAL

      Source sequence(s)
      AF071260
      UniProtKB/Swiss-Prot
      Q4PR80, Q9YGT0
      Related
      ENSDARP00000132869.1, ENSDART00000170593.3
      Conserved Domains (1) summary
      pfam00046
      Location:218271
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      2172335..2173459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)