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    or71al2 odorant receptor, family 71, subfamily AL, member 2 [ Danio rerio (zebrafish) ]

    Gene ID: 554777, updated on 4-Jan-2025

    Summary

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    Official Symbol
    or71al2provided by ZNC
    Official Full Name
    odorant receptor, family 71, subfamily AL, member 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010308-22
    See related
    Ensembl:ENSDARG00000041033 AllianceGenome:ZFIN:ZDB-GENE-010308-22
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    or4.1; olfr4.1; or119-2; or15.38; zgc:195165; zgc:195250; si:ch211-133d24.18
    Summary
    Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in olfactory rosette. Orthologous to several human genes including OR1A1 (olfactory receptor family 1 subfamily A member 1); OR1A2 (olfactory receptor family 1 subfamily A member 2); and OR1C1 (olfactory receptor family 1 subfamily C member 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See or71al2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (31332539..31333815)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (31451741..31453040)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene odorant receptor, family 71, subfamily AS, member 1 Neighboring gene odorant receptor 15.37 Neighboring gene odorant receptor, family 40, subfamily A, member 1 Neighboring gene odorant receptor, family 42, subfamily E, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Odorant receptor gene regulation: implications from genomic organization. Kratz E, et al. Trends Genet, 2002 Jan. PMID 11750698
    2. Hierarchical regulation of odorant receptor gene choice and subsequent axonal projection of olfactory sensory neurons in zebrafish. Sato Y, et al. J Neurosci, 2007 Feb 14. PMID 17301169, Free PMC Article
    3. Silencing of odorant receptor genes by G protein βγ signaling ensures the expression of one odorant receptor per olfactory sensory neuron. Ferreira T, et al. Neuron, 2014 Feb 19. PMID 24559675, Free PMC Article
    4. Analysis and characterization of an odorant receptor gene cluster in the zebrafish genome. Dugas JC, et al. Genomics, 2001 Jan 1. PMID 11161797
    5. Evolutionary dynamics of olfactory receptor genes in fishes and tetrapods. Niimura Y, et al. Proc Natl Acad Sci U S A, 2005 Apr 26. PMID 15824306, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    odorant receptor 119-2
    Names
    Dr3OR15.29
    odorant receptor, family 4, member 1
    odorant receptor, family F, subfamily 119, member 2
    olfactory receptor protein 4.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039622.2 → NP_001034711.1  odorant receptor 119-2

      See identical proteins and their annotated locations for NP_001034711.1

      Status: PROVISIONAL

      Source sequence(s)
      BC163823
      UniProtKB/TrEMBL
      A0A1D5NSV8, F6NWI4, Q2PRD5
      Related
      ENSDARP00000142929.1, ENSDART00000173915.2
      Conserved Domains (2) summary
      cd14964
      Location:62 → 84
      7tm_GPCRs; TM helix 2 [structural motif]
      cl28897
      Location:37 → 299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      31332539..31333815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157689.5 → XP_005157746.1  odorant receptor 119-2 isoform X1

      See identical proteins and their annotated locations for XP_005157746.1

      UniProtKB/TrEMBL
      A0A1D5NSV8, F6NWI4, Q2PRD5
      Related
      ENSDARP00000114241.1, ENSDART00000134933.2
      Conserved Domains (2) summary
      cd14964
      Location:62 → 84
      7tm_GPCRs; TM helix 2 [structural motif]
      cl28897
      Location:37 → 299
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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