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    decr1 2,4-dienoyl CoA reductase 1, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 436717, updated on 9-Dec-2024

    Summary

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    Official Symbol
    decr1provided by ZNC
    Official Full Name
    2,4-dienoyl CoA reductase 1, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-142
    See related
    Ensembl:ENSDARG00000003869 AllianceGenome:ZFIN:ZDB-GENE-040718-142
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fe38b07; zgc:92356; wu:fe38b07
    Summary
    Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Is expressed in cardiac ventricle. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See decr1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (36748561..36760156)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (36794677..36806272)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene collagen, type VI, alpha 4a Neighboring gene phosphoinositide-3-kinase, regulatory subunit 4 Neighboring gene calbindin 1 Neighboring gene purine nucleoside phosphorylase 4b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Anxiety-related behavior and associated brain transcriptome and epigenome alterations in adult female zebrafish exposed to atrazine during embryogenesis. Horzmann KA, et al. Chemosphere, 2022 Dec. PMID 36126741
    2. Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. Fukuda R, et al. EMBO Rep, 2020 Aug 5. PMID 32648304, Free PMC Article
    3. Regulation of cytochrome P450 expression in a novel liver cell line from zebrafish (Brachydanio rerio). Miranda CL, et al. Arch Biochem Biophys, 1993 Sep. PMID 8373170
    4. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Ayobahan SU, et al. Sci Rep, 2019 Apr 29. PMID 31036921, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 2,4-dienoyl-CoA reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial
    NP_001002444.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002444.2 → NP_001002444.2  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

      Status: VALIDATED

      Source sequence(s)
      EH504463, EH572714, EH595644
      UniProtKB/TrEMBL
      A0A8M1N0E2
      Related
      ENSDARP00000120922.1, ENSDART00000139069.2
      Conserved Domains (2) summary
      PRK07677
      Location:57 → 302
      PRK07677; short chain dehydrogenase; Provisional
      cd05369
      Location:55 → 301
      TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      36748561..36760156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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