get4 guided entry of tail-anchored proteins factor 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: get4provided by ZNC
Official Full Name: guided entry of tail-anchored proteins factor 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5399
See related: Ensembl:ENSDARG00000024398 AllianceGenome:ZFIN:ZDB-GENE-030131-5399
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cee; fd15h01; wu:fd15h01
Summary: Predicted to be involved in protein insertion into ER membrane. Predicted to be part of BAT3 complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human GET4 (guided entry of tail-anchored proteins factor 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (11262954..11306770, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (11224651..11268467, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in protein insertion into ER membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein insertion into ER membrane	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of BAT3 complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Golgi to ER traffic protein 4 homolog

Names: conserved edge expressed protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199907.1 → NP_001186836.1 Golgi to ER traffic protein 4 homolog

Status: VALIDATED

Source sequence(s)

CU459216

UniProtKB/TrEMBL

A0A8M1NXG1, F1R3Y3

Related

ENSDARP00000034770.7, ENSDART00000036989.8

Conserved Domains (1) summary

pfam04190
Location:51 → 288

DUF410; Protein of unknown function (DUF410)