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    mvb12ba multivesicular body subunit 12Ba [ Danio rerio (zebrafish) ]

    Gene ID: 767667, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mvb12baprovided by ZNC
    Official Full Name
    multivesicular body subunit 12Baprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-372
    See related
    Ensembl:ENSDARG00000091619 AllianceGenome:ZFIN:ZDB-GENE-060929-372
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam125ba; zgc:152929
    Summary
    Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Predicted to act upstream of or within protein transport. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Predicted to be active in late endosome. Orthologous to human MVB12B (multivesicular body subunit 12B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mvb12ba in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (5163395..5243094, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (4671452..4750939, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137495547 Neighboring gene LIM homeobox transcription factor 1, beta a Neighboring gene pre-B-cell leukemia homeobox 3a Neighboring gene MAPK associated protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution and Expression of Paxillin Genes in Teleost Fish. Jacob AE, et al. PLoS One, 2016. PMID 27806088, Free PMC Article
    2. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC152929

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ESCRT I complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    multivesicular body subunit 12Ba
    Names
    family with sequence similarity 125, member B, duplicate a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076606.2 → NP_001070074.2  multivesicular body subunit 12Ba isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU856517
      UniProtKB/TrEMBL
      Q08CM0
      Related
      ENSDARP00000109861.2, ENSDART00000130576.3

    2. NM_001431133.1 → NP_001418062.1  multivesicular body subunit 12Ba isoform 1

      Status: VALIDATED

      Source sequence(s)
      CU856517
      UniProtKB/TrEMBL
      A0A8M6Z6D7, Q08CM0

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      5163395..5243094 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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