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    sap18 Sin3A-associated protein [ Danio rerio (zebrafish) ]

    Gene ID: 393693, updated on 9-Dec-2024

    Summary

    Official Symbol
    sap18provided by ZNC
    Official Full Name
    Sin3A-associated proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1679
    See related
    Ensembl:ENSDARG00000057854 AllianceGenome:ZFIN:ZDB-GENE-040426-1679
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73118
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human SAP18 (Sin3A associated protein 18). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See sap18 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (21266684..21268601, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (21455815..21457732, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene hyperpolarization activated cyclic nucleotide-gated potassium channel 5 Neighboring gene potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like Neighboring gene spindle and kinetochore associated complex subunit 3 Neighboring gene uncharacterized LOC101884374 Neighboring gene large tumor suppressor kinase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC73118

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    histone deacetylase complex subunit SAP18
    Names
    sin3-associated polypeptide

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200720.2NP_957014.1  histone deacetylase complex subunit SAP18

      See identical proteins and their annotated locations for NP_957014.1

      Status: VALIDATED

      Source sequence(s)
      BI709589, BX511129, EH440312
      UniProtKB/TrEMBL
      A9JT48, Q6PC41
      Related
      ENSDARP00000075051.5, ENSDART00000080604.6
      Conserved Domains (1) summary
      pfam06487
      Location:24137
      SAP18; Sin3 associated polypeptide p18 (SAP18)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      21266684..21268601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394749.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      136443..138358 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)