bop1 BOP1 ribosomal biogenesis factor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bop1provided by ZNC
Official Full Name: BOP1 ribosomal biogenesis factorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030219-109
See related: Ensembl:ENSDARG00000063627 AllianceGenome:ZFIN:ZDB-GENE-030219-109
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: id:ibd1283; zgc:154135; si:ch211-251g8.2; si:ch211-251g8.4
Summary: Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and regulation of cell cycle. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Is expressed in head; immature eye; midbrain hindbrain boundary; optic tectum; and somite. Orthologous to human BOP1 (BOP1 ribosomal biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (2929770..3056068, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (2989475..3115150, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

fc64d06.x1 (e-PCR)
- UniSTS:203966

fj77f12.y1 (e-PCR)
- UniSTS:199873

fb79d08.y1 (e-PCR)
- UniSTS:191483

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ribonucleoprotein complex binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IEA Inferred from Electronic Annotation more info
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in regulation of cell cycle	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of PeBoW complex	IBA Inferred from Biological aspect of Ancestor more info
part_of PeBoW complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of preribosome, large subunit precursor	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ribosome biogenesis protein bop1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077735.2 → NP_001071203.1 ribosome biogenesis protein bop1

See identical proteins and their annotated locations for NP_001071203.1

Status: VALIDATED

Source sequence(s)

BX255894

UniProtKB/Swiss-Prot

A0JMQ0, Q1LXV3

Related

ENSDARP00000120969.3, ENSDART00000137020.5

Conserved Domains (4) summary

COG2319
Location:432 → 776

WD40; WD40 repeat [General function prediction only]

cd00200
Location:438 → 776

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

pfam08145
Location:174 → 432

BOP1NT; BOP1NT (NUC169) domain

sd00039
Location:447 → 483

7WD40; WD40 repeat [structural motif]