nudt9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nudt9provided by ZNC
Official Full Name: nudix (nucleoside diphosphate linked moiety X)-type motif 9provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2669
See related: Ensembl:ENSDARG00000087927 AllianceGenome:ZFIN:ZDB-GENE-040426-2669
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fu33g07; sb:cb392; zgc:63924; wu:fj16b09; wu:fu33g07
Summary: Predicted to enable ADP-ribose diphosphatase activity. Involved in regulation of cyclic nucleotide-gated ion channel activity. Is expressed in several structures, including Kupffer's vesicle; axial chorda mesoderm; axis; nervous system; and trigeminal placode. Orthologous to human NUDT9 (nudix hydrolase 9). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (26223374..26232773)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (26092503..26101902)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ADP-ribose diphosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of cyclic nucleotide-gated ion channel activity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cyclic nucleotide-gated ion channel activity	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: ADP-ribose pyrophosphatase, mitochondrial

NP_998517.2

EC 3.6.1.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213352.2 → NP_998517.2 ADP-ribose pyrophosphatase, mitochondrial precursor

Status: VALIDATED

Source sequence(s)

EH449789, EH523281, FP016144

UniProtKB/TrEMBL

A0A8M1PPR4, F1QL34

Related

ENSDARP00000106416.2, ENSDART00000128284.3

Conserved Domains (1) summary

cd03670
Location:145 → 331

ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...