RT1-O1 RT1 class Ib, locus O1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: RT1-O1provided by RGD
Official Full Name: RT1 class Ib, locus O1provided by RGD
Primary source: RGD:3501
See related: EnsemblRapid:ENSRNOG00000076074 AllianceGenome:RGD:3501
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RT1-O; Qlikea
Summary: Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I. Predicted to be located in lumenal side of endoplasmic reticulum membrane and phagocytic vesicle membrane. Predicted to be part of MHC class I protein complex. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 427.0), Spleen (RPKM 349.9) and 9 other tissues See more
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Genomic context

Location:: 20p12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (2659937..2662341)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (2655116..2657520)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (3160535..3162939)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of peptide antigen via MHC class I	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of MHC class I protein complex	IEA Inferred from Electronic Annotation more info
located_in lumenal side of endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in phagocytic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RT1 class Ib, locus O1

Names: RT1 class Ib gene, H2-Q-like, grc region; RT1 class Ib, locus H2-Q-like, grc region

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.