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    Mpzl3 myelin protein zero-like 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363054, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mpzl3provided by RGD
    Official Full Name
    myelin protein zero-like 3provided by RGD
    Primary source
    RGD:1310980
    See related
    EnsemblRapid:ENSRNOG00000068913 AllianceGenome:RGD:1310980
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310980
    Summary
    Predicted to act upstream of or within extracellular matrix organization and hair cycle. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MPZL3 (myelin protein zero like 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 48.9), Brain (RPKM 22.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mpzl3 in Genome Data Viewer
    Location:
    8q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (54257235..54277422)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (45360475..45380662)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (49354257..49374444)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene CD3 epsilon subunit of T-cell receptor complex Neighboring gene myelin protein zero-like 2 Neighboring gene small nucleolar RNA, H/ACA box 41B Neighboring gene junction adhesion molecule like Neighboring gene 5S ribosomal RNA Neighboring gene sodium voltage-gated channel beta subunit 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    myelin protein zero-like protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108760.1NP_001102230.1  myelin protein zero-like protein 3 precursor

      See identical proteins and their annotated locations for NP_001102230.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473975
      UniProtKB/TrEMBL
      A0A8I6B1H0, A6J426, D3ZBX8
      Related
      ENSRNOP00000111355.1, ENSRNOT00000155407.1
      Conserved Domains (2) summary
      cd00096
      Location:3337
      Ig; Ig strand A [structural motif]
      cl11960
      Location:33137
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      54257235..54277422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)