ncs-7 EF-hand domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ncs-7
Official Full Name: EF-hand domain-containing protein
Primary source: WormBase:WBGene00015867
Locus tag: CELE_C16H3.1
See related: AllianceGenome:WB:WBGene00015867
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of signal transduction. Is expressed in neurons and vulval muscle. Orthologous to several human genes including KCNIP1 (potassium voltage-gated channel interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ncs-7 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 7

Sequence:: Chromosome: X; NC_003284.9 (17614545..17619622)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C16H3.1 (e-PCR)
- UniSTS:319047

STS6-244 (e-PCR)
- UniSTS:242631

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of signal transduction	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: EF-hand domain-containing protein

NP_001360661.1

Partially confirmed by transcript evidence

NP_001360662.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

17614545..17619622

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001373632.3 → NP_001360661.1 EF-hand domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0ILQ4

Conserved Domains (1) summary

COG5126
Location:37 → 200

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
NM_001373633.4 → NP_001360662.1 EF-hand domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A4V0IK35

Conserved Domains (1) summary

COG5126
Location:59 → 222

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]