U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    dnj-11 DnaJ homolog subfamily C member 2 [ Caenorhabditis elegans ]

    Gene ID: 177419, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    dnj-11
    Official Full Name
    DnaJ homolog subfamily C member 2
    Primary source
    WormBase:WBGene00001029
    Locus tag
    CELE_F38A5.13
    See related
    AllianceGenome:WB:WBGene00001029
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable Hsp70 protein binding activity and ribosome binding activity. Predicted to be involved in 'de novo' cotranslational protein folding. Located in cytosol. Is expressed in several structures, including intestine; muscle cell; nervous system; pharynx; and reproductive system. Orthologous to human DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See dnj-11 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (6585871..6588186)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Ufm1-specific protease Neighboring gene TraB domain-containing protein Neighboring gene Galectin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Receptor L-domain domain-containing protein Neighboring gene Nematode Specific Peptide family, group B

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genomic analysis of stress response against arsenic in Caenorhabditis elegans. Sahu SN, et al. PLoS One, 2013. PMID 23894281, Free PMC Article
    2. Coordination of cell proliferation and cell fate determination by CES-1 snail. Yan B, et al. PLoS Genet, 2013 Oct. PMID 24204299, Free PMC Article
    3. Control of apoptosis by asymmetric cell division. Hatzold J, et al. PLoS Biol, 2008 Apr 8. PMID 18399720, Free PMC Article
    4. An actin-based viscoplastic lock ensures progressive body-axis elongation. Lardennois A, et al. Nature, 2019 Sep. PMID 31462781, Free PMC Article
    5. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables Hsp70 protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 'de novo' cotranslational protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in 'de novo' cotranslational protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of translational fidelity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DnaJ homolog subfamily C member 2
    NP_501006.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      6585871..6588186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068605.7 → NP_501006.1  DnaJ homolog subfamily C member 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501006.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q94216
      Conserved Domains (4) summary
      smart00717
      Location:536 → 584
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      COG5269
      Location:61 → 441
      ZUO1; Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones]
      cd00167
      Location:536 → 582
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00226
      Location:98 → 167
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous