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    bli-2 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191611, updated on 27-Dec-2024

    Summary

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    Official Symbol
    bli-2
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00000252
    Locus tag
    CELE_F59E12.12
    See related
    AllianceGenome:WB:WBGene00000252
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in external encapsulating structure. Predicted to be part of collagen trimer. Is expressed in cuticle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bli-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (5651394..5652434, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene BLOC-1-related complex subunit 5 Neighboring gene Anaphase-promoting complex subunit 13 Neighboring gene ncRNA Neighboring gene putative serine/threonine-protein kinase zyg-1 Neighboring gene Bromo domain-containing protein Neighboring gene Alpha-(1,3)-fucosyltransferase fut-3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tetraspanin protein (TSP-15) is required for epidermal integrity in Caenorhabditis elegans. Moribe H, et al. J Cell Sci, 2004 Oct 15. PMID 15454573
    2. LG II balancer chromosomes in Caenorhabditis elegans: mT1(II;III) and the mIn1 set of dominantly and recessively marked inversions. Edgley ML, et al. Mol Genet Genomics, 2001 Nov. PMID 11713668
    3. Roller mutants of the nematode Caenorhabditis elegans. Higgins BJ, et al. Mol Gen Genet, 1977 Jan 7. PMID 834177
    4. Genetic and Phenotypic Characterization of Roller Mutants of CAENORHABDITIS ELEGANS. Cox GN, et al. Genetics, 1980 Jun. PMID 17249038, Free PMC Article
    5. Cuticle collagen genes. Expression in Caenorhabditis elegans. Johnstone IL. Trends Genet, 2000 Jan. PMID 10637627

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of collagen and cuticulin-based cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in collagen and cuticulin-based cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in external encapsulating structure ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_495104.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5651394..5652434 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062703.5 → NP_495104.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495104.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01904
      Conserved Domains (3) summary
      pfam01391
      Location:179 → 229
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:15 → 60
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
      PHA03169
      Location:138 → 278
      PHA03169; hypothetical protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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