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    snu-66 uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 179140, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snu-66
    Official Full Name
    uncharacterized protein
    Primary source
    WormBase:WBGene00017605
    Locus tag
    CELE_F19F10.9
    See related
    AllianceGenome:WB:WBGene00017605
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mRNA cis splicing, via spliceosome and maturation of 5S rRNA. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Orthologous to human SART1 (spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See snu-66 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (7571950..7575670, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CW domain-containing protein Neighboring gene ncRNA Neighboring gene DUF2769 domain-containing protein Neighboring gene Beta-Casp domain-containing protein Neighboring gene ETS class transcription factor Neighboring gene HAT C-terminal dimerization domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for SNU66 in maintaining 5' splice site identity during spliceosome assembly. Sarka K, et al. RNA, 2024 May 16. PMID 38443114, Free PMC Article
    2. The ubiquitin-like protein Hub1/UBL-5 functions in pre-mRNA splicing in Caenorhabditis elegans. Kolathur KK, et al. FEBS Lett, 2023 Feb. PMID 36480405, Free PMC Article
    3. Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation. Baytek G, et al. Biotechniques, 2022 May. PMID 35297663
    4. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    5. Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. Crawford ED, et al. Cell Death Differ, 2012 Dec. PMID 22918439, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A role for SNU66 in maintaining 5' splice site identity during spliceosome assembly.
      Title: A role for SNU66 in maintaining 5' splice site identity during spliceosome assembly.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA cis splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in maturation of 5S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_504952.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class snu; SNU (yeast Small NUclear ribonucleoprotein associated) homolog

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7571950..7575670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072551.6 → NP_504952.1  uncharacterized protein CELE_F19F10.9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504952.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01524
      Conserved Domains (1) summary
      pfam03343
      Location:52 → 784
      SART-1; SART-1 family
    Nucleotide Protein
    Heading Accession and Version

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