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    twk-31 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176572, updated on 9-Dec-2024

    Summary

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    Official Symbol
    twk-31
    Official Full Name
    Potassium channel domain-containing protein
    Primary source
    WormBase:WBGene00006683
    Locus tag
    CELE_Y47D3B.5
    See related
    AllianceGenome:WB:WBGene00006683
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See twk-31 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    23
    Sequence:
    Chromosome: III; NC_003281.10 (11410678..11424661)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene IGFBP N-terminal domain-containing protein Neighboring gene Glycosyltransferase family 92 protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene EB domain-containing protein Neighboring gene Processed sterol regulatory element binding protein sbp-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SLO-2, a K+ channel with an unusual Cl- dependence. Yuan A, et al. Nat Neurosci, 2000 Aug. PMID 10903569
    2. Alternative splicing regulation during C. elegans development: splicing factors as regulated targets. Barberan-Soler S, et al. PLoS Genet, 2008 Feb 29. PMID 18454200, Free PMC Article
    3. Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms. Buckingham SD, et al. Trends Pharmacol Sci, 2005 Jul. PMID 15939489
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium ion leak channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Potassium channel domain-containing protein
    NP_001022884.1
    • Confirmed by transcript evidence
    NP_001359517.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11410678..11424661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027713.5 → NP_001022884.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022884.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6EUT8
      Conserved Domains (1) summary
      pfam07885
      Location:226 → 283
      Ion_trans_2; Ion channel

    2. NM_001372661.2 → NP_001359517.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XX01
      Conserved Domains (1) summary
      pfam07885
      Location:226 → 282
      Ion_trans_2; Ion channel
    Nucleotide Protein
    Heading Accession and Version

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