U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nmgp-1 Neuronal Membrane GlycoProtein [ Caenorhabditis elegans ]

    Gene ID: 184437, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    nmgp-1
    Official Full Name
    Neuronal Membrane GlycoProtein
    Primary source
    WormBase:WBGene00017437
    Locus tag
    CELE_F13H8.4
    See related
    AllianceGenome:WB:WBGene00017437
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in neuron projection development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cephalic sheath cell; neurons; somatic nervous system; tail ganglion; and ventral ganglion. Used to study depressive disorder. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Orthologous to human GPM6A (glycoprotein M6A); GPM6B (glycoprotein M6B); and PLP1 (proteolipid protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See nmgp-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (6260857..6262524)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Mitochondrial prohibitin complex protein 2 Neighboring gene protein of unknown function DB domain-containing protein Neighboring gene Lipase_GDSL domain-containing protein Neighboring gene MSP domain-containing protein Neighboring gene Inosine/uridine-preferring nucleoside hydrolase domain-containing protein Neighboring gene SET domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Neuronal membrane glycoprotein (nmgp-1) gene deficiency affects chemosensation-related behaviors, dauer exit and egg-laying in Caenorhabditis elegans. Fernández EM, et al. J Neurochem, 2022 Jan. PMID 34816431
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Neuronal membrane glycoprotein (nmgp-1) gene deficiency affects chemosensation-related behaviors, dauer exit and egg-laying in Caenorhabditis elegans.
      Title: Neuronal membrane glycoprotein (nmgp-1) gene deficiency affects chemosensation-related behaviors, dauer exit and egg-laying in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Neuronal Membrane GlycoProtein
    NP_495253.2
    • Product from WormBase gene class nmgp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6260857..6262524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062852.7 → NP_495253.2  Neuronal Membrane GlycoProtein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495253.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19430
      Conserved Domains (1) summary
      cl02417
      Location:23 → 193
      Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools