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    M01G12.9 Decapping nuclease [ Caenorhabditis elegans ]

    Gene ID: 187385, updated on 9-Dec-2024

    Summary

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    Official Symbol
    M01G12.9
    Official Full Name
    Decapping nuclease
    Primary source
    WormBase:WBGene00010822
    Locus tag
    CELE_M01G12.9
    See related
    AllianceGenome:WB:WBGene00010822
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping and nuclear-transcribed mRNA catabolic process. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See M01G12.9 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (12108588..12112505, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RNA-directed RNA polymerase Neighboring gene Decapping nuclease Neighboring gene pseudo Neighboring gene Decapping nuclease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA 5'-diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in NAD-cap decapping IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear-transcribed mRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Decapping nuclease
    NP_493059.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12108588..12112505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060658.4 → NP_493059.2  Decapping nuclease [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493059.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62317
      Conserved Domains (1) summary
      pfam12815
      Location:294 → 355
      CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    Nucleotide Protein
    Heading Accession and Version

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