pqn-59 Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59 [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: pqn-59
Official Full Name: Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59
Primary source: WormBase:WBGene00004143
Locus tag: CELE_R119.4
See related: AllianceGenome:WB:WBGene00004143
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be active in cytoplasm and nucleus. Is expressed widely. Orthologous to several human genes including UBAP2L (ubiquitin associated protein 2 like). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See pqn-59 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 6

Sequence:: Chromosome: I; NC_003279.8 (379071..381902, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans.
Title: PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans.
PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryos.
Title: PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryos.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

R119.4 (e-PCR)
- UniSTS:305693

R119.3 (e-PCR)
- UniSTS:317794

STS1-148 (e-PCR)
- UniSTS:241634

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59

NP_490727.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

379071..381902 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_058326.8 → NP_490727.1 Prion-like (glutamine/asparagine-rich) domain bearing protein pqn-59 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_490727.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O61708

Conserved Domains (1) summary

cd14277
Location:31 → 68

UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins