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    Gm19410 predicted gene, 19410 [ Mus musculus (house mouse) ]

    Gene ID: 100502846, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Gm19410provided by MGI
    Official Full Name
    predicted gene, 19410provided by MGI
    Primary source
    MGI:MGI:5011595
    See related
    Ensembl:ENSMUSG00000109372 AllianceGenome:MGI:5011595
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 2.3), frontal lobe adult (RPKM 1.9) and 2 other tissues See more
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    Genomic context

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    See Gm19410 in Genome Data Viewer
    Location:
    8 A4; 8 21.16 cM
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (36232399..36285202)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (35765287..35818048)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700015I17 gene Neighboring gene STARR-positive B cell enhancer ABC_E3773 Neighboring gene predicted gene, 35021 Neighboring gene predicted gene, 40492 Neighboring gene elongation factor Tu, mitochondrial pseudogene Neighboring gene claudin 23 Neighboring gene RIKEN cDNA 5430403N17 gene Neighboring gene STARR-seq mESC enhancer starr_21188

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100502846

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370844.1 → NP_001357773.1  uncharacterized protein LOC100502846 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129211, AC146295
      Consensus CDS
      CCDS90388.1
      UniProtKB/TrEMBL
      A0A140LJC7
      Related
      ENSMUSP00000147162.2, ENSMUST00000207505.2
      Conserved Domains (7) summary
      smart00192
      Location:187 → 218
      LDLa; Low-density lipoprotein receptor domain class A
      smart00135
      Location:1391 → 1432
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00179
      Location:263 → 301
      EGF_CA; Calcium-binding EGF-like domain
      COG3386
      Location:1693 → 1763
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      cd00112
      Location:990 → 1024
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00058
      Location:1367 → 1407
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      pfam14670
      Location:1822 → 1856
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      36232399..36285202
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509234.5 → XP_006509297.1  uncharacterized protein LOC100502846 isoform X1

      Conserved Domains (7) summary
      smart00192
      Location:187 → 218
      LDLa; Low-density lipoprotein receptor domain class A
      smart00135
      Location:1391 → 1432
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00179
      Location:263 → 301
      EGF_CA; Calcium-binding EGF-like domain
      COG3386
      Location:1693 → 1763
      YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
      cd00112
      Location:990 → 1024
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam00058
      Location:1367 → 1407
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      pfam14670
      Location:1822 → 1856
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    RNA

    1. XR_004934736.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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