U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Defb23 defensin beta 23 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 641621, updated on 9-Dec-2024

    Summary

    Official Symbol
    Defb23provided by RGD
    Official Full Name
    defensin beta 23provided by RGD
    Primary source
    RGD:1560097
    See related
    EnsemblRapid:ENSRNOG00000023477 AllianceGenome:RGD:1560097
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB129 (defensin beta 129). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 3.2) and Lung (RPKM 0.8) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Defb23 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (161383615..161390685, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (140923474..140927715, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (147928201..147932413, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 20 open reading frame 96 Neighboring gene zinc finger CCHC-type containing 3 Neighboring gene defensin beta 20 Neighboring gene defensin beta 22

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    beta-defensin 129
    Names
    beta-defensin 23

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037518.2NP_001032607.1  beta-defensin 129 precursor

      See identical proteins and their annotated locations for NP_001032607.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6KHN6, F7EVM5, Q32ZG9
      Related
      ENSRNOP00000031138.1, ENSRNOT00000032030.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      161383615..161390685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284514.1XP_063140584.1  beta-defensin 129 isoform X1

      UniProtKB/TrEMBL
      A6KHN6, F7EVM5, Q32ZG9