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    Trim80 tripartite motif protein 80 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287824, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Trim80provided by RGD
    Official Full Name
    tripartite motif protein 80provided by RGD
    Primary source
    RGD:1311352
    See related
    EnsemblRapid:ENSRNOG00000028812 AllianceGenome:RGD:1311352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Trim47; Trim47l
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in immune system process. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 159.5) and Liver (RPKM 8.2) See more
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    Genomic context

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    See Trim80 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101181797..101190122)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (100682826..100691152)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (103984644..104004060)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ATP synthase peripheral stalk subunit d Neighboring gene potassium channel tetramerization domain containing 2 Neighboring gene solute carrier family 16 member 5 Neighboring gene armadillo repeat containing 7 Neighboring gene 5', 3'-nucleotidase, cytosolic

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tripartite motif protein 80
    Names
    E3 ubiquitin/ISG15 ligase TRIM25
    gene overexpressed in astrocytoma
    tripartite motif protein 47
    tripartite motif protein 47-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408610.1 → NP_001395539.1  tripartite motif protein 80

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      Q5BIZ7
      Related
      ENSRNOP00000060665.2, ENSRNOT00000065292.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      101181797..101190122
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039087797.1 → XP_038943725.1  tripartite motif protein 80 isoform X1

      UniProtKB/TrEMBL
      F1LMT9
      Conserved Domains (5) summary
      TIGR00599
      Location:63 → 161
      rad18; DNA repair protein rad18
      cd16609
      Location:90 → 134
      RING-HC_TRIM65_C-IV; RING finger, HC subclass, found in tripartite motif-containing protein TRIM65 and similar proteins
      cd19769
      Location:228 → 273
      Bbox2_TRIM16-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM16, TRIM29, TRIM47 and similar proteins
      cd19802
      Location:177 → 221
      Bbox1_TRIM8-like; B-box-type 1 zinc finger found in tripartite motif-containing proteins, TRIM8, TRIM16, TRIM25, TRIM29, TRIM44, TRIM47 and similar proteins
      cl02614
      Location:464 → 639
      SPRY; SPRY domain

    2. XM_039087798.1 → XP_038943726.1  tripartite motif protein 80 isoform X2

      UniProtKB/TrEMBL
      F1LMT9
      Conserved Domains (5) summary
      TIGR00599
      Location:63 → 161
      rad18; DNA repair protein rad18
      cd16609
      Location:90 → 134
      RING-HC_TRIM65_C-IV; RING finger, HC subclass, found in tripartite motif-containing protein TRIM65 and similar proteins
      cd19769
      Location:228 → 273
      Bbox2_TRIM16-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM16, TRIM29, TRIM47 and similar proteins
      cd19802
      Location:177 → 221
      Bbox1_TRIM8-like; B-box-type 1 zinc finger found in tripartite motif-containing proteins, TRIM8, TRIM16, TRIM25, TRIM29, TRIM44, TRIM47 and similar proteins
      cl02614
      Location:459 → 634
      SPRY; SPRY domain
    Nucleotide Protein Strain
    Heading Accession and Version

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