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    nhr-89 Nuclear hormone receptor family member nhr-89 [ Caenorhabditis elegans ]

    Gene ID: 184026, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-89
    Official Full Name
    Nuclear hormone receptor family member nhr-89
    Primary source
    WormBase:WBGene00003679
    Locus tag
    CELE_E03H4.13
    See related
    AllianceGenome:WB:WBGene00003679
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-89 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (12439936..12441253, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Hexosyltransferase Neighboring gene Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Neighboring gene Nuclear hormone receptor family member nhr-169 Neighboring gene B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear hormone receptor family member nhr-89
    NP_493155.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12439936..12441253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060754.4 → NP_493155.1  Nuclear hormone receptor family member nhr-89 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493155.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02235, O17752
      Conserved Domains (3) summary
      smart00399
      Location:7 → 75
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      smart00430
      Location:150 → 292
      HOLI; Ligand binding domain of hormone receptors
      cl00281
      Location:121 → 160
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O02235.2

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