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    ZK858.6 Transmembrane 9 superfamily member [ Caenorhabditis elegans ]

    Gene ID: 172739, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK858.6
    Official Full Name
    Transmembrane 9 superfamily member
    Primary source
    WormBase:WBGene00014119
    Locus tag
    CELE_ZK858.6
    See related
    AllianceGenome:WB:WBGene00014119
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein localization to membrane. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be active in membrane. Is expressed in intestine. Orthologous to human TM9SF4 (transmembrane 9 superfamily member 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK858.6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    11
    Sequence:
    Chromosome: I; NC_003279.8 (9138406..9145632, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein maternal effect lethal 26;Protein roadkill Neighboring gene TM2 domain-containing protein ZK858.5 Neighboring gene ncRNA Neighboring gene tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 Neighboring gene Amino acid transporter transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in intracellular monoatomic cation homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein localization to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane 9 superfamily member
    NP_001129804.1
    • Partially confirmed by transcript evidence
    NP_001367071.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9138406..9145632 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001136332.3 → NP_001129804.1  Transmembrane 9 superfamily member [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001129804.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3WFW5
      Conserved Domains (1) summary
      pfam02990
      Location:90 → 613
      EMP70; Endomembrane protein 70

    2. NM_001380961.1 → NP_001367071.1  Transmembrane 9 superfamily member [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YTF9
      Conserved Domains (1) summary
      pfam02990
      Location:53 → 576
      EMP70; Endomembrane protein 70
    Nucleotide Protein
    Heading Accession and Version

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