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    ceh-7 Homeobox protein ceh-7 [ Caenorhabditis elegans ]

    Gene ID: 174391, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ceh-7
    Official Full Name
    Homeobox protein ceh-7
    Primary source
    WormBase:WBGene00000432
    Locus tag
    CELE_C34C6.8
    See related
    AllianceGenome:WB:WBGene00000432
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in I3 neuron; head neurons; and in male. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ceh-7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (8703315..8703829, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein Neighboring gene Sphingosine kinase 1 Neighboring gene TPR_REGION domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Serpentine receptor class gamma-15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Caenorhabditis elegans homeobox gene expressed in the male tail, a link between pattern formation and sexual dimorphism? Kagoshima H, et al. Dev Genes Evol, 1999 Jan. PMID 9914419
    2. Caenorhabditis elegans has scores of homoeobox-containing genes. Bürglin TR, et al. Nature, 1989 Sep 21. PMID 2571091
    3. The NK-2 class homeodomain factor CEH-51 and the T-box factor TBX-35 have overlapping function in C. elegans mesoderm development. Broitman-Maduro G, et al. Development, 2009 Aug. PMID 19605496, Free PMC Article
    4. Genome-wide analysis of sex-enriched gene expression during C. elegans larval development. Thoemke K, et al. Dev Biol, 2005 Aug 15. PMID 15987632
    5. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Homeobox protein ceh-7
    NP_495848.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8703315..8703829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063447.4 → NP_495848.1  Homeobox protein ceh-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495848.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P20270, Q18430
      Conserved Domains (1) summary
      pfam00046
      Location:26 → 79
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20270.2

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